Sunday, May 24, 2020

Potential Therapeutic Treatment Options For Psychiatric...

Since the early 1990 s discovery of the naturally occurring endocannabinnoid receptors CB1 and CB2 in the human brain, preclinical and clinical trials focusing on plant derived cannabinnoids have begun to regain momentum. This paper focuses on the cannabinnoids Cannabidiol (CBD) and Delta-9-Tetrahydrocannabinol (Δ9-THC) as potential therapeutic treatment options for psychiatric disorders. It contains an overview of studies and trials which used CBD and Δ9-THC to treat memory disorders, Schizophrenia, anxiety, and depression, as well as early information CBD s neuroprotective properties as possible treatment for Parkinson s disease, Huntington’s disease, Neonatal Ischaemia/newborn hypoxic-ichaemic brain damage, and Multiple Sclerosis. Cannabinoids in the Brain: Potential Therapeutic Use of Cannabidiol Versus Delta-9-Tetrahydrocannabinol in the Treatment of Psychiatric Disorders The neuromodulatory lipids endocannabinnoids, along with their receptors, are found naturally throughout the body, and have a primary goal of assisting with homeostasis. They help to carry out a myriad of physiological processes including mood, appetite, memory, and the sensation of pain (Sagie et al., 2013). Since the discovery of the naturally occurring receptors in the early 1990 s, plant derived cannabinnoids have gone under increasingly extensive clinical trials for their possible therapeutic uses (Kumar et al., 2001). 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